SARS-CoV (SARS coronavirus) is the virus that causes severe acute respiratory syndrome (SARS). Coronaviruses encode papain-like proteases (PLpro) that are often multifunctional enzymes with protease activity to process the viral replicase polyprotein and deubiquitinating (DUB)/deISGylating activity, which is hypothesized to modify the innate immune response to infection.

4'-O-Methylbavachalcone
		Cat. No.: HY-N1910
4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC of 10.1 μM.
Purity: Clinical Data: Size:	>98% No Development Reported 5 mg, 10 mg
Chloroquine phosphate
		Cat. No.: HY-17589
Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Chloroquine diphosphate is an antimalarial and anti-inflammatory drug widely used to treat malaria and rheumatoid arthritis.
Purity: Clinical Data: Size:	99.94% Launched 10 mM × 1 mL, 100 mg
PLpro inhibitor
		Cat. No.: HY-17542
PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) with IC50 of 2.6 uM
Purity: Clinical Data: Size:	99.79% No Development Reported 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg
6-Thioguanine
		Cat. No.: HY-13765
6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC s of 25 μM and 50 40 μM for Plpros and recombinant human…
Purity: Clinical Data: Size:	>98.0% Launched 10 mM × 1 mL, 100 mg, 500 mg
GRL0617
		Cat. No.: HY-117043
GRL0617 is a potent, selective and competitive noncovalent inhibitor of severe acute respiratory syndrome (SARS-CoV) papain-like protease (PLpro)/deubiquitinase, with an IC of 50 0.6 μM, and with a K of 0.49 μM.
Purity: Clinical Data: Size:	>98% No Development Reported 1 mg, 5 mg
Scutellarein
		Cat. No.: HY-N0752
Scutellarin, a main active ingredient extracted from Erigeron breviscapus (Vant.) Hand-Mazz., has been wildly used to treat acute cerebral infarction and paralysis induced by cerebrovascular diseases.
Purity: Clinical Data: Size:	99.02% No Development Reported 10 mM × 1 mL, 2 mg, 5 mg, 10 mg, 25 mg, 50 mg

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